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Guideview >  HOT RFQ  > Guidechem's Chemicals Hot RFQ - 4th Week of December 2025

Guidechem's Chemicals Hot RFQ - 4th Week of December 2025

Explore Guidechem’s HOT RFQs for the 4th week of December 2025, featuring trending chemical purchase requests across Asia, Europe, America, and Global markets for buyers and suppliers. GuideView3 MIN READDecember 29, 2025

Guidechem's HOT RFQ – 4th Week of December 2025

Guidechem's HOT RFQ – 4th Week of December 2025

Column Purpose & Target

Guidechem HOT RFQ is a weekly column that highlights the most valuable and trending chemical purchase requests from our platform. It helps both buyers and suppliers stay informed and act quickly in the global chemical trade.

Frequency: Weekly, published every Thursday.

Benefits

  • Buyers: Discover popular RFQs and learn how to submit high-quality RFQs to attract more supplier quotes.
  • Suppliers: Access timely global demand insights and learn to reply efficiently to quality RFQs to increase order rates.

Weekly HOT RFQs

?? Asia

HOT RFQ ?? Asia - 4th week December 2025.png

Carbazole (CAS: 86-74-8)
Country: India
Quantity: 1 MT
A nitrogen-containing aromatic compound widely used in pharmaceuticals and dyes.

5-Bromo-3-chloropyridine-2-carbonitrile (CAS: 945557-04-0)
Country: India
Quantity: 1 MT
An important heterocyclic intermediate for agrochemical and pharmaceutical synthesis.

1-Naphthaleneacetic acid (CAS: 86-87-3)
Country: China
Quantity: 1 T
A plant growth regulator commonly used in agricultural applications.

3-Amino-5-Bromo-Pyridine-2-Carbonitrile (CAS: 573675-27-1)
Country: China
Quantity: 1000 KG
A key pyridine derivative used as a pharmaceutical intermediate.

Retatrutide (CAS: 2381089-83-2)
Country: China
Quantity: 10 MG
A novel peptide compound under research for metabolic disorders.

N-Methyl-2-pyrrolidone (CAS: 872-50-4)
Country: China
Quantity: 10 G
A high-boiling polar aprotic solvent used in chemical processing.

Lithium tri-tert-butoxyaluminum hydride (CAS: 17476-04-9)
Country: India
Quantity: 1 L
A selective reducing agent widely used in organic synthesis.

Sodium gluconate (CAS: 527-07-1)
Country: Pakistan
Quantity: 10 KG
A chelating agent used in food, pharmaceutical, and construction industries.

5-tert-Butylisophthalic acid (CAS: 2359-09-3)
Country: China
Quantity: 5 KG
An aromatic acid used in specialty polymer and resin production.

Bupropion Hydrochloride (CAS: 31677-93-7)
Country: India
Quantity: 25 G
An antidepressant active pharmaceutical ingredient.

Zanubrutinib (CAS: 1691249-45-2)
Country: India
Quantity: 25 G
A BTK inhibitor used in oncology drug development.

Fluconazole (CAS: 86386-73-4)
Country: Pakistan
Quantity: 50 KG
A broad-spectrum antifungal pharmaceutical ingredient.

Azithromycin (CAS: 83905-01-5)
Country: Pakistan
Quantity: 200 KG
A macrolide antibiotic widely used in infection treatment.

α-Ethylaminopentiophenone (hydrochloride) (CAS: 18268-16-1)
Country: China
Quantity: 1 KG
A synthetic compound used in chemical research applications.

O-Desmethyltramadol (CAS: 80456-81-1)
Country: China
Quantity: 10 G
An active metabolite of tramadol for pharmaceutical research.

Pregabalin (CAS: 148553-50-8)
Country: China
Quantity: 1 KG
An anticonvulsant drug used for neuropathic pain management.

Cannabigerol (CAS: 25654-31-3)
Country: China
Quantity: 1 KG
A non-psychoactive cannabinoid used in medical research.

Mirogabalin (CAS: 1138245-13-2)
Country: China
Quantity: 100 G
A gabapentinoid drug for neuropathic pain treatment.

Xantphos (CAS: 161265-03-8)
Country: Japan
Quantity: 100 KG
A bidentate phosphine ligand used in catalytic reactions.

Polyethylene-polyamines (CAS: 68131-73-7)
Country: China
Quantity: 20000 KG
A polymeric amine used in resins, coatings, and water treatment.

N-Methylphenethylamine (CAS: 589-08-2)
Country: Iran
Quantity: 500 KG
An organic amine used as a chemical intermediate.

Lumateperone (CAS: 313368-91-1)
Country: India
Quantity: 25 G
An atypical antipsychotic active pharmaceutical ingredient.

Osimertinib mesylate (CAS: 1421373-66-1)
Country: India
Quantity: 25 G
A third-generation EGFR inhibitor used in cancer therapy.

2',3'-Di-O-acetyl-5'-deoxy-5-fluorocytidine (CAS: 161599-46-8)
Country: India
Quantity: 60 KG
A nucleoside derivative used in pharmaceutical manufacturing.

Mercury (CAS: 7439-97-6)
Country: Sudan
Quantity: 5 MT
A heavy metal used in industrial and laboratory applications.

Chromocene (CAS: 1271-24-5)
Country: China
Quantity: 1 T
An organometallic compound used in research and catalysis.

N-cyclopropylguanidine hydrochloride (CAS: 207974-05-8)
Country: Korea
Quantity: 10 G
A guanidine derivative used as a pharmaceutical intermediate.

Ammonium carbonate (CAS: 506-87-6)
Country: Kampuchea (Cambodia)
Quantity: 1400 KG
An inorganic salt used in food processing and chemical synthesis.

1H-Imidazole-5-methanol, 1-[(1R)-1-phenylethyl]- (CAS: 226930-17-2)
Country: China
Quantity: 100 KG
An imidazole derivative used in pharmaceutical research.


?? America

HOT RFQ ?? America - 4th week December 2025.png

Dextromethorphan hydrobromide (CAS: 125-69-9)
Country: Brazil
Quantity: 3 G
An antitussive pharmaceutical ingredient used in cough suppressant formulations.

Pyrazolam (CAS: 39243-02-2)
Country: Australia
Quantity: 40 G
A triazolobenzodiazepine compound supplied for research purposes.

Testosterone enanthate (CAS: 315-37-7)
Country: United States
Quantity: 2 KG
A long-acting testosterone ester used in pharmaceutical manufacturing.

Dimethocaine (CAS: 94-15-5)
Country: Australia
Quantity: 100 MT
A synthetic local anesthetic compound used in chemical research.

Methylclonazepam (CAS: 5527-71-9)
Country: United States
Quantity: 1 KG
A benzodiazepine derivative supplied for analytical and research use.

Flutazolam (CAS: 27060-91-9)
Country: United States
Quantity: 1 KG
A triazolobenzodiazepine compound used in pharmaceutical research.

Somatropin (CAS: 12629-01-5)
Country: United States
Quantity: 100 μL
A recombinant human growth hormone used in biomedical research.

Isopropylbenzylamine (CAS: 102-97-6)
Country: United States
Quantity: 1 KG
An organic amine used as an intermediate in chemical synthesis.

Chlordiazepoxide and phenobarbital (5:3) (CAS: 63917-56-6)
Country: United States
Quantity: 2 G
A pharmaceutical combination compound referenced for research use.

Chlordiazepoxide hydrochloride (CAS: 438-41-5)
Country: United States
Quantity: 2 G
A benzodiazepine API used in pharmaceutical and analytical research.


?? Europe

HOT RFQ ?? Europe- 4th week December 2025.png

Dimethocaine (CAS: 94-15-5)
Country: Iceland
Quantity: 10 KG
A local anesthetic compound used in pharmaceutical and research applications.

4-MPM hydrochloride (CAS: 1998216-41-3)
Country: Germany
Quantity: 500 G
A synthetic stimulant-related compound for laboratory research use.

Estradiol (CAS: 57-91-0)
Country: France
Quantity: 10 G
A natural estrogen hormone widely used in pharmaceutical manufacturing.

O-Desmethyltramadol (CAS: 73986-53-5)
Country: United Kingdom
Quantity: 100 KG
An active metabolite of tramadol used in pharmaceutical research.

4F-MPH (CAS: 1354631-33-6)
Country: Italy
Quantity: 1 G
A fluorinated stimulant compound supplied for analytical research purposes.

HEXEN (CAS: 18410-62-3)
Country: Slovakia
Quantity: 1 KG
A synthetic psychoactive compound intended for chemical research use.

Yttrium(III) butoxide solution (CAS: 111941-71-0)
Country: Russia
Quantity: 1 KG
An organometallic precursor used in materials science and catalyst research.

2-ethyl-2-[[(1-oxooleyl)oxy]methyl]-1,3-propanediyl dioleate (CAS: 57675-44-2)
Country: Russia
Quantity: 20 T
A fatty acid ester used in lubricants, cosmetics, and industrial formulations.

Liquid Red Mercury (CAS: 20720-76-7)
Country: Austria
Quantity: 1 KG
A mercury-containing material referenced in specialized industrial inquiries.

Oxacyclotridecane-2,13-dione (CAS: 85483-04-1)
Country: France
Quantity: 1 G
A macrocyclic compound used in specialty chemical research.


?? Global

HOT RFQ ?? Global - 4th week December 2025.png

Isopropylbenzylamine (CAS: 102-97-6)
Country: Global
Quantity: 10 G
An organic amine commonly used as an intermediate in chemical synthesis.

Favipiravir-5-hydroxy (CAS: 1492021-29-0)
Country: Global
Quantity: 1 G
A metabolite-related compound used in antiviral drug research.

Retatrutide (CAS: 2381089-83-2)
Country: Global
Quantity: 1 G
A next-generation peptide under investigation for metabolic disease treatment.

INDOLAROME (CAS: 18096-62-3)
Country: Global
Quantity: 2 KG
An indole-based compound used in fragrance and specialty chemical applications.

Testosterone acetate (CAS: 1045-69-8)
Country: Global
Quantity: 1 KG
A testosterone ester used in pharmaceutical and biochemical research.

5-Bromo-1H-benzimidazole (CAS: 4887-88-1)
Country: Global
Quantity: 1 KG
A heterocyclic compound used as an intermediate in pharmaceutical synthesis.


For Buyers – How to Post an RFQ

Why post an RFQ on Guidechem?

  • Reach thousands of verified global suppliers
  • Increase visibility and get faster quotes
  • Benefit from transaction assurance and logistic support
How to Post an RFQ on Guidechem?

Posting a Request for Quotation (RFQ) on Guidechem is simple and efficient. Follow these steps to connect with the best suppliers worldwide:

  1. Register and Log In to your Guidechem account.
  2. Click on the “Post an RFQ” button and fill in the product details, including quantity and country of origin.
  3. Receive competitive quotes from suppliers and choose the best match for your needs.

Post RFQ

Whether you're sourcing specialty chemicals or bulk raw materials, Guidechem is here to help! Connect with trusted suppliers and streamline your procurement process today. ??


For Suppliers – How to Leverage HOT RFQs

Why monitor HOT RFQs?

  • Stay ahead by spotting active global demands
  • Match with serious buyers faster
  • Improve quote success rate with well-targeted replies

Tips to Respond Efficiently:

  1. Reply within 24 hours of RFQ publication
  2. Include detailed quotation: lead time, packaging, incoterms
  3. Highlight factory certifications and supply capacity
  4. Attach documents such as COA, MSDS, product photos

* If you’d like your inquiry to be featured next week, make sure to post a complete RFQ with valid contact and product details.


How to Post an RFQ on Guidechem?

  HOT RFQ          
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